Predictive Modeling Of Drug Sensitivity

Author: Ranadip Pal
Publisher: Academic Press
ISBN: 012805431X
Size: 17.49 MB
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This book is an ideal reference for computer scientists, engineers, computational biologists, and mathematicians who want to understand and apply multiple approaches and methods to drug sensitivity modeling.

British Journal Of Neurosurgery

Author:
Publisher:
ISBN:
Size: 11.37 MB
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NEURO-ONCOLOGY Comparison of in vitro Cloning Assays for Drug Sensitivity
Testing of Human Brain Tumours MICHAEL E. ... Identification of accurate
predictive models of drug sensitivity will require correlative in vivo and in vitro
studies.

Comprehensive Systems Biomedicine

Author: Pietro Lio
Publisher: Frontiers E-books
ISBN: 2889193748
Size: 80.94 MB
Format: PDF, ePub, Mobi
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To fill gaps in the datasets we developed and applied predictive models. The
results can be interpreted at the ... of drug responses in cancer subtypes. To
deconvolute, model, and understand drug sensitivity relies on systems-wide
approaches ...

Translational Pain Research

Author: Lawrence Kruger
Publisher: CRC Press
ISBN: 1439812101
Size: 62.55 MB
Format: PDF, ePub, Docs
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... in the field of drug discovery and development since the sensitivity and
predictive validity of animal models can only be established through extensive
testing in many contexts. For these reasons, the rat and mouse models will
continue to be ...

Bioinformatics

Author: Information Resources Management Association
Publisher: IGI Global
ISBN: 146663605X
Size: 38.41 MB
Format: PDF, Docs
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Chemosensitivity. Prediction. of. Tumours. based. on. Expression,. miRNA,. and.
Proteomics. Data. I. Tsamardinos ... the G150 value of a drug (an indicator of the
response to the drug), regression methods for constructing predictive models of ...

Antimalarial Chemotherapy

Author: Philip J. Rosenthal
Publisher: Springer Science & Business Media
ISBN: 1592591116
Size: 46.59 MB
Format: PDF, Kindle
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The efficacy of antifolate antimalarial combinations in Africa: a predictive model
based on pharmacodynamic and ... Le Bras J, Deloron P. In vitor study of drug
sensitivity of Plasmodium falciparum: evaluation of a new semi-micro test.

Antitargets And Drug Safety

Author: Laszlo Urban
Publisher: John Wiley & Sons
ISBN: 3527673660
Size: 76.60 MB
Format: PDF, ePub, Docs
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... Mueller, S.O., and Dooley, S. (2009) Extracellular matrix modulates sensitivity
of hepatocytes to fibroblastoid dedifferentiation ... 85 86 87 88 90 91 92 84 Lake,
B.G. 154 7 In Vitro Models for the Prediction of Drug-Induced Liver Injury in Lead
 ...

Pharmacokinetics And Pharmacodynamics Of Abused Drugs

Author: Steven B. Karch, MD, FFFLM
Publisher: CRC Press
ISBN: 9781420054606
Size: 48.82 MB
Format: PDF, ePub
View: 3137
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The model was equally accurate in predicting the presence (sensitivity = 94.4%)
and absence of ethanol (specificity = 92.6%); overall predictive efficiency was
93.3%. The analysis also resulted in a subset of 17 variables that were the best ...

The Control Of Tumour Growth And Its Biological Bases

Author: W. Davis
Publisher: Springer Science & Business Media
ISBN: 9780898386035
Size: 59.27 MB
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In such studies cell lines are acceptable models. In vitro techniques seem also to
be the most promising approach for predicting drug sensitivity of human tumours
and for ... The history of predictive tests The long history of predictive ...